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The consensus among the Godot development team is that these are false positives . This often happens with open-source software when a new release hasn't yet established a "reputation" with Microsoft's automated scanning algorithms.

While experienced developers often recognize these as false alarms, such warnings can significantly deter new users or those in corporate environments with strict security policies. Resolution and Recommendations 110612

Several users reported that the official Godot_v4.5-stable_win64.exe was being flagged by Microsoft’s security software. The consensus among the Godot development team is

The Godot team has provided specific guidance for users encountering this issue: 110612

Users are encouraged to upload the binary to the Microsoft Security Intelligence file submission portal to report it as a false positive. This helps the engine's binaries gain trusted status more quickly.