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The number primarily refers to a medical research paper titled "Exogenous sickle erythrocytes combined with vascular disruption trigger disseminated tumor vaso-occlusion and lung tumor regression" . Article Overview: JCI Insight 125535

: The treatment demonstrated significant effectiveness in causing lung tumor regression in experimental models. 125535

: This highlights a potential "therapeutic repurposing" of sickle cell biology to combat cancer by starving tumors of their oxygen and nutrient supply. Alternative Reference The number primarily refers to a medical research

In environmental science, the number appears as in Volume 384 of the Journal of Environmental Management (2025). Alternative Reference In environmental science

: The researchers found that this combination triggers a "vaso-occlusive" event—essentially a controlled blockage of the blood vessels feeding the tumor—which leads to tumor cell death.

: The study uses "exogenous" (externally introduced) sickle red blood cells in combination with a vascular-disrupting agent to target the blood supply of tumors.