In 2015, Takeda Pharmaceuticals agreed to a massive $2.37 billion settlement to resolve approximately 9,000 bladder cancer claims in the U.S..

Check your records to see how long you took Actos and at what dosage.

While the drug remains on the market in the U.S., the FDA prescribing information now includes warnings about the potential bladder cancer risk. 3. Warning Signs and Symptoms

Studies indicated that the risk increased with higher cumulative doses and longer duration of use (specifically more than 12 months).