Atopy

: Upon re-exposure, allergens cross-link IgE on the surface of mast cells, causing degranulation and the release of inflammatory mediators like histamine and leukotrienes. 2. The Atopic March

: Sensitization through inflamed skin can lead to early-onset food allergies. : Upon re-exposure, allergens cross-link IgE on the

Atopy typically follows a predictable chronological progression: : Upon re-exposure

: Systemic immune priming eventually leads to upper and lower airway inflammation. 3. Key Management Strategies : Upon re-exposure, allergens cross-link IgE on the