: This mission is almost entirely a boss battle against a giant demonic construct. You must target the glowing weak points on its legs to make it collapse, then jump onto its back to attack the core.
: Clearing the game on "Dante Must Die" mode unlocks Super Characters (Nero, Dante, V, and Vergil), which provide infinite Devil Trigger.
: Nero gets access to the Mega Buster (Mega Man crossover), Pasta Breaker , Sweet Surrender , and Gerbera GP01 .
: Completing this mission unlocks the unmissable story achievement "End of the Line" . Strategic Tips
: Before starting Mission 6, customize Nero’s loadout. Using the Hidden Power addition or specific magazines can help power up your long-range attacks like Blue Rose.
: On Mission 09 (Genesis), you can find the actual "Secret Mission 6." You must destroy all enemies without being hit. Using V's Royal Fork skill is highly recommended here to finish enemies instantly once their health is low.
: Adds the Cavaliere R , a modified version of his motorcycle weapon.