: Standard console releases are often locked to specific regions (e.g., NTSC-U for North America, PAL for Europe, NTSC-J for Japan). A "Region Free" ISO allows the game to be played on a console from any region, typically through soft-modding or specialized hardware. Platform Context

: Playing the game on PC via emulators like RPCS3 (PS3).

While Mafia II was officially released for , "ISO" files are most commonly associated with: