), where a carbon atom is triple-bonded to a nitrogen atom. While often used interchangeably with "nitrile rubber" (NBR) in consumer contexts like gloves, the term encompasses a broad range of molecules critical for drug discovery, material science, and chemical synthesis.
: Nitriles are susceptible to both nucleophilic and electrophilic attacks. nitril
: Utilizing Aldoxime Dehydratases as biocatalysts to create nitriles from biogenic resources under mild conditions. ), where a carbon atom is triple-bonded to a nitrogen atom
The defining feature of a nitrile is the . The electronegativity of the nitrogen atom combined with the electropositivity of the carbon atom creates a highly polarized triple bond. This polarity makes nitriles versatile intermediates in organic chemistry, allowing them to undergo various transformations. : Utilizing Aldoxime Dehydratases as biocatalysts to create
Traditional nitrile synthesis often involved harsh conditions or toxic cyanides. Modern research focuses on "greener" methods: