[s2e21] The Vegas Renormalization 〈Direct Link〉

Howard's ringtone is "She Blinded Me with Science," which was the theme song for the show's original, unaired pilot.

Back in Pasadena, Sheldon plans a glorious weekend of being alone, eating Indian food that the others can't have due to allergies or personal distaste (paneer). [S2E21] The Vegas Renormalization

They lure Howard to the buffet with the promise of "shrimp the size of babies' arms," where Mikayla reels him in by complaining about the lack of brisket. Howard's ringtone is "She Blinded Me with Science,"

Sheldon ends up taking over Penny's bed and annoying her into singing "Soft Kitty" because he feels "homesick". Sheldon ends up taking over Penny's bed and

Leonard and Raj take a depressed Howard to Las Vegas to help him forget his heartbreak. When Howard refuses to leave his hotel room—spending his time stalking Leslie on Facebook and posting "depressing Twitters"—the guys decide to take drastic measures.

In (Season 2, Episode 21), the gang splits up for two very different types of "social experimentation" after Leslie Winkle dumps Howard. The Vegas "Jewish Girlfriend Experience"

Howard eventually realizes she’s a professional but, instead of being offended, is deeply touched that his friends would do that for him and continues the "experience". Sheldon's "Fortress of Solitude"