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The infection progresses through four distinct stages if left untreated: Syphilis - StatPearls - NCBI Bookshelf

Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum . Historically known as "the great imitator," it is notorious for symptoms that mimic many other diseases, making it difficult to recognize without testing. The Rising Crisis sifelis.zip

After decades of decline, syphilis is experiencing a major resurgence globally. : U.S. cases rose 80% between 2018 and 2022. The infection progresses through four distinct stages if

: Newborn cases (congenital syphilis) increased over 10 times from 2012 to 2022. sifelis.zip

: Men who have sex with men (MSM) and young adults (ages 20–35) remain the most affected populations. Stages and Symptoms